rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/Asn heterozygous genotypes might be recognized as potential genetic markers modifying susceptibility to bladder cancer in Belarus.
|
25089939 |
2014 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The current meta-analysis indicated that the Lys751Gln polymorphism in the XPD gene might be a risk factor for bladder cancer.
|
24535265 |
2014 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
For ERCC2 Lys751Gln, individuals who carried the variant heterozygote Lys/Gln or homozygote Gln/Gln had a significantly increased bladder cancer risk, compared with the wild genotype Lys/Lys (OR=1.10, 95 % CI=1.03-1.18).
|
24504678 |
2014 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
For ERCC2 Asp312Asn, individuals with the Asn allele were associated with a 1.29-fold (95 % CI=1.13-1.48) increased risk of bladder cancer.
|
24504678 |
2014 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We found the Lys751Gln was associated with increased bladder cancer risk only under the recessive model (OR = 1.14, 95% CI = 1.01-1.29).
|
24347488 |
2014 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Overall, the variant allele of Asp312Asn polymorphism was associated with an increased risk of bladder cancer (Asn/Asn vs. Asp/Asp: OR = 1.51, 95% CI = 1.19-1.91; Asp/Asn vs. Asp/Asp: OR = 1.23, 95% CI = 1.12-1.35; recessive model: OR = 1.33, 95% CI = 1.10-1.61; dominant model: OR = 1.32, 95% CI = 1.14-1.52; and allele comparing: OR = 1.26, 95% CI = 1.11-1.42).
|
24347488 |
2014 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These associations were: two SNPs rs1799793 and rs13181 in the ERCC2 gene and lung cancer (recessive model) and rs1805794 in the NBN gene and bladder cancer (dominant model).
|
21864546 |
2012 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These associations were: two SNPs rs1799793 and rs13181 in the ERCC2 gene and lung cancer (recessive model) and rs1805794 in the NBN gene and bladder cancer (dominant model).
|
21864546 |
2012 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In this work, we have conducted a case-control study in order to assess the effect of tobacco and three genetic polymorphisms in XPC, ERCC2 and ERCC5 genes (rs2228001, rs13181 and rs17655) in bladder cancer development in Tunisia.
|
21426550 |
2011 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Polymorphic variants of XPD, at codon 312 (rs1799793), 751 (rs13181) and promoter-114 (rs3810366), were chosen to be studied for their association with bladder cancer susceptibility in a central Taiwanese population.
|
19846926 |
2009 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Polymorphic variants of XPD, at codon 312 (rs1799793), 751 (rs13181) and promoter-114 (rs3810366), were chosen to be studied for their association with bladder cancer susceptibility in a central Taiwanese population.
|
19846926 |
2009 |
rs3810366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphic variants of XPD, at codon 312 (rs1799793), 751 (rs13181) and promoter-114 (rs3810366), were chosen to be studied for their association with bladder cancer susceptibility in a central Taiwanese population.
|
19846926 |
2009 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that the XPD Asp312Asn but not Lys751Gln polymorphism may be more genetically susceptible to bladder cancer development.
|
19492231 |
2009 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that the XPD Asp312Asn but not Lys751Gln polymorphism may be more genetically susceptible to bladder cancer development.
|
19492231 |
2009 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Subtle but significant cancer risk was observed for the XPD Asp 312 Asn polymorphism in bladder cancer (for Asp/Asn versus Asp/Asp: OR, 1.24; 95% CI, 1.06-1.46).
|
18349268 |
2008 |
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In multifactor dimensionality reduction (MDR) analysis, the five-factor model including smoking, CCNH V270A, ERCC6 M1097V, RAD23B A249V and XPD D312N had the best ability to predict bladder cancer risk.
|
17728339 |
2007 |
rs776223836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In multifactor dimensionality reduction (MDR) analysis, the five-factor model including smoking, CCNH V270A, ERCC6 M1097V, RAD23B A249V and XPD D312N had the best ability to predict bladder cancer risk.
|
17728339 |
2007 |
rs13181
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We found that the A allele of XPD Arg156Arg (C22541A) and the C allele of XPD Lys751Gln (A35931C) is associated with increased risk of bladder cancer (adjusted odds ratio = 1.54 and 95% confidence interval = 1.19-2.01, 1.65, and 1.12-2.73, respectively).
|
17693188 |
2007 |